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Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP)

  • Published:2021-02 Issue:2 Volume:1865 Page:129800
  • ISSN:0304-4165
  • Container-title:Biochimica et Biophysica Acta (BBA) - General Subjects
  • language:en
  • Short-container-title:Biochimica et Biophysica Acta (BBA) - General Subjects

Author:

Ho Joseph D.,Lee Matthew R.,Rauch Charles T.,Aznavour Kristen,Park Jonathan S.,Luz John G.,Antonysamy Stephen,Condon Bradley,Maletic Milan,Zhang Aiping,Hickey Michael J.,Hughes Norman E.,Chandrasekhar Srinivasan,Sloan Ashley V.,Gooding Karen,Harvey Anita,Yu Xiao-Peng,Kahl Steven D.,Norman Bryan H.

Funder

U.S. Department of Energy

Argonne National Laboratory

Office of Science

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference43 articles.

1. The eicosanoids and their biochemical mechanisms of action;Smith;Biochem. J.,1989

2. Prostanoids in health and disease;Smyth;J. Lipid Res.,2009

3. Prostaglandins and leukotrienes: advances in eicosanoid biology;Funk;Science,2001

4. Prostaglandins and inflammation;Ricciotti;Arterioscler. Thromb. Vasc. Biol.,2011

5. Anti-inflammatory drugs in the 21st century;Rainsford;Subcell. Biochem.,2007

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