Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment

Author:

Balboni Andrea,Govoni Marzia,Rossi Valentina,Roberti Marinella,Cavalli Andrea,Di Stefano Giuseppina,Manerba Marcella

Funder

Roberto and Cornelia Pallotti's Legacy for Cancer Research

Università di Bologna

Associazione Italiana per la Ricerca sul Cancro

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference43 articles.

1. Cancer as a metabolic disease: implication for novel therapeutics;Seyfried;Carcinogenesis,2014

2. Tumor metabolism: cancer cells give and take lactate;Semenza;J. Clin. Invest.,2008

3. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation;Lunt;Annu. Rev. Cell Dev. Biol.,2011

4. The enhancement of glycolysis regulates pancreatic cancer metastasis;Yang;Cell. Mol. Life Sci.,2020

5. Metabolic regulation of apoptosis in cancer;Matsuura;Int. Rev. Cell Mol. Biol.,2016

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