Automated synthesis of 1-[11C]acetoacetate on a TRASIS AIO module

Author:

Solingapuram Sai Kiran Kumar,Donald Gage H.,Almaguel Frankis,Neth Bryan,Hughes Timothy M.,Tremblay Sebastien,Castellano Christian-Alexandre,Cunnane Stephen C.,Jorgensen Matthew J.,Craft Suzanne,Mintz Akiva

Funder

Hartman Foundation

American Cancer Society Mentored Research Scholar

NIH Vervet Research Colony

NIH AD Center

Clinical Translational Science Institute

Publisher

Elsevier BV

Subject

Radiation

Reference29 articles.

1. AIO, T., 2014. TRASIS AllinOne GMP Universal Radiosynthesis Unit, 〈http://www.trasis.com/pages/all_in_one.html〉, p. TRASIS automated instrument.

2. [11C] acetoacetate utilization by breast and prostate tumors: a PET and biodistribution study in mice;Authier;Mol. Imaging Biol.,2008

3. PET study of [11C]-acetoacetate kinetics in rat brain during dietary treatments affecting ketosis;Bentourkia;Am. J. Physiol. – Endocrinol. Metab.,2009

4. β-hydroxybutyrate oxidation is reduced and hepatic balance of ketone bodies and free fatty acids is unaltered in carnitine-depleted, pivalate-treated rats;Bianchi;J. Nutr.,1996

5. Lower brain 18F-fluorodeoxyglucose uptake but normal 11C-acetoacetate metabolism in mild Alzheimer's disease dementia;Castellano;J. Alzheimer's Dis.,2015

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