Fully automated preparation of [11C]choline and [18F]fluoromethylcholine using TracerLab synthesis modules and facilitated quality control using analytical HPLC

Author:

Shao Xia,Hockley Brian G.,Hoareau Raphaël,Schnau Paul L.,Scott Peter J.H.

Funder

University of Michigan Cyclotron and Radiochemistry group gratefully acknowledges funding for this research from the Office of Biological and Environmental Research (BER) of the Office of Science (SC), U. S. Department of Energy

Publisher

Elsevier BV

Subject

Radiation

Reference14 articles.

1. A simple, versatile, low-cost and remotely operated apparatus for [11C]acetate, [11C]choline, [11C]methionine and [11C]PIB synthesis;Cheung;Appl. Radiat. Isot.,2009

2. Synthesis and evaluation of 18F-labeled choline analogs as oncologic PET tracers;DeGrado;J. Nucl. Med.,2001

3. Synthesis and evaluation of 18F-labeled choline as an oncologic tracer for positron emission tomography: initial findings in prostate cancer;DeGrado;Cancer Res.,2001

4. Imaging of brain tumor, lung cancer, esophagus cancer, colon cancer, prostate cancer and bladder cancer with [C-11]choline;Hara;J. Nucl. Med.,1997

5. Automated synthesis of [11C]choline, a positron-emitting tracer for tumor imaging;Hara;Appl. Radiat. Isot.,1999

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