Phase II trial of trastuzumab in women with advanced or recurrent, HER2-positive endometrial carcinoma: A Gynecologic Oncology Group study

Author:

Fleming Gini F.,Sill Michael W.,Darcy Kathleen M.,McMeekin D. Scott,Thigpen J. Tate,Adler Lisa M.,Berek Jonathan S.,Chapman Julia A.,DiSilvestro Paul A.,Horowitz Ira R.,Fiorica James V.

Funder

Genentech

National Cancer Institute

Publisher

Elsevier BV

Subject

Obstetrics and Gynaecology,Oncology

Reference25 articles.

1. Trastuzumab—mechanism of action and use in clinical practice;Hudis;N. Engl. J. Med.,2007

2. HER-2 is an independent prognostic factor in endometrial cancer: association with outcome in a large cohort of surgically staged patients;Morrison;J. Clin. Oncol.,2006

3. Analysis of HER-2/neu amplification in endometrial carcinoma by chromogenic in situ hybridization. Correlation with fluorescence in situ hybridization,HER-2/neu, p53 and Ki-67 protein expression, and outcome;Peirâo;Mod. Pathol.,2004

4. An exploratory analysis of HER-2 amplification and overexpression in advanced endometrial carcinoma: a Gynecologic Oncology Group study;Grushko;Gynecol. Oncol.,2008

5. Optimal flexible designs in phase II clinical trials;Chen;Stat. Med.,1998

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