MLH1-methylated endometrial cancer under 60 years of age as the “sentinel” cancer in female carriers of high-risk constitutional MLH1 epimutation

Author:

Hitchins Megan P.,Alvarez Rocio,Zhou Lisa,Aguirre Francesca,Dámaso Estela,Pineda Marta,Capella Gabriel,Wong Justin J.-L.,Yuan Xiaopu,Ryan Shawnia R.,Sathe Devika S.,Baxter Melanie D.,Cannon Timothy,Biswas Rakesh,DeMarco Tiffani,Grzelak Doreen,Hampel Heather,Pearlman Rachel

Funder

Ministerio de Ciencia e Innovación

Ministerio de Asuntos Económicos y Transformación Digital, Gobierno de España

National Institutes of Health

National Cancer Institute

Ministerio de Economía y Competitividad

Cedars-Sinai Medical Center

Publisher

Elsevier BV

Subject

Obstetrics and Gynecology,Oncology

Reference47 articles.

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3. An updated review of microsatellite instability in the era of next-generation sequencing and precision medicine;Yamamoto;Semin. Oncol.,2019

4. Combined microsatellite instability, MLH1 methylation analysis, and immunohistochemistry for Lynch syndrome screening in endometrial cancers from GOG210: an NRG oncology and gynecologic oncology group study;Goodfellow;J. Clin. Oncol.,2015

5. hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis;Esteller;Am. J. Pathol.,1999

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