Defined covalent attachment of three cancer drugs to DNA origami increases cytotoxicity at nanomolar concentration

Author:

Navarro Natalia,Aviñó Anna,Domènech Òscar,Borrell Jordi H.,Eritja Ramon,Fàbrega Carme

Funder

Instituto de Salud Carlos III

Ministerio de Ciencia e Innovación

CIBER-BBN

European Regional Development Fund

Seventh Framework Programme

Espana Ministerio de Ciencia e Innovacion

European Cooperation in Science and Technology

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Materials Science,Biomedical Engineering,Molecular Medicine,Medicine (miscellaneous),Bioengineering

Reference59 articles.

1. Nucleic acid junctions and lattices;Seeman;J Theor Biol,1982

2. Folding DNA to create nanoscale shapes and patterns;Rothemund;Nature,2006

3. Recent advances in self-assembled DNA nanostructures for bioimaging;Yang;ACS Appl Bio Mater,2022

4. DNA origami;Dey;Nat Rev Methods Primers,2021

5. DNA origami as a DNA repair nanosensor at the single-molecule level;Tintoré;Angew Chem,2013

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