Recuperative effect of metformin loaded polydopamine nanoformulation promoting EZH2 mediated proteasomal degradation of phospho-α-synuclein in Parkinson’s disease model

Author:

Sardoiwala Mohammed Nadim,Srivastava Anup K.,Kaundal Babita,Karmakar Surajit,Choudhury Subhasree Roy

Funder

Science and Engineering Research Board

Department of Biotechnology

Publisher

Elsevier BV

Subject

Pharmaceutical Science,General Materials Science,Biomedical Engineering,Molecular Medicine,Medicine (miscellaneous),Bioengineering

Reference55 articles.

1. Epidemiology of Parkinson's disease and movement disorders in India: problems and possibilities;Muthane;The Journal of the Association of Physicians of India.,2007

2. Parkinson disease;Poewe;Nature Reviews Disease Primers.,2017

3. Novel antibodies to phosphorylated alpha-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes;Rutherford;Acta neuropathologica communications.,2016

4. Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain;Devi;The Journal of biological chemistry.,2008

5. Advances in epigenetics and epigenomics for neurodegenerative diseases;Qureshi;Curr Neurol Neurosci Rep.,2011

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