Large-scale stereoselective enzymatic ketone reduction with in situ product removal via polymeric adsorbent resins

Author:

Vicenzi Jeffrey T.,Zmijewski Milton J.,Reinhard Matthew R.,Landen Bryan E.,Muth William L.,Marler Paul G.

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Biochemistry,Biotechnology,Bioengineering

Reference18 articles.

1. Application of a practical biocatalytic reduction to an enantioselective synthesis of the 5H-2,3-benzodiazepine LY300164;Anderson;J. Am. Chem. Soc.,1995

2. Zmijewski, M., Vicenzi, J., Landen, B., Muth, W., Marler, P., and Anderson, B. Enantioselective reduction of 3,4-methylene dioxyphenyl acetone using PitCandida famata and Zygosaccharomyces rouxii. Appl. Microbiol. Biotechnol. in press

3. Continuous production of 3-fluror-l-alanine with alanine dehydrogenase;Ohshima;Biotechnol. Bioeng.,1989

4. Continuous enzymatic transformation in an enzyme membrane reactor with simultaneous NAD(H) regeneration;Wichmann;Biotechnol. Bioeng.,1981

5. Enzyme-catalyzed organic synthesis: NAD(P)H cofactor regeneration using ethanol/alcohol dehydrogenase/aldehyde dehydrogenase and methanol/alcohol dehydrogenase/aldehyde dehydrogenase/formate dehydrogenase;Wong;J. Org. Chem.,1982

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