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A mechanistic investigation into the microbial chiral inversion of 2-arylpropionic acids using deuterated derivatives of 2-phenylpropionic acid

  • Published:1998-03 Issue:4 Volume:22 Page:281-287
  • ISSN:0141-0229
  • Container-title:Enzyme and Microbial Technology
  • language:en
  • Short-container-title:Enzyme and Microbial Technology

Author:

Rhys-Williams W.,McCarthy F.,Baker J.,Hung Y.-F.,Thomason M.J.,Lloyd A.W.,Hanlon G.W.

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,Biochemistry,Biotechnology,Bioengineering

Reference29 articles.

1. The metabolic chiral inversion of the 2-aryl propionic acids — a novel route with pharmacological consequences;Hutt;J. Pharm. Pharmacol.,1983

2. Pharmacological aspects of chiral non-steroidal antiiflammatory drugs;Muller;Fund. Clin. Pharmacol.,1990

3. Metabolism of ibuprofen;Mills;Xenobiotica,1973

4. Metabolic stereoisomeric inversion of 2-arylpropionic acids. On the mechanism of ibuprofen epimerization in rats;Chen;Biochim. Biophys. Acta,1990

5. Optical isomerization mechanism of R-(−)-hydratroacid derivatives;Nakamura;J. Pharmacobiol. Dyn.,1981

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