Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL
Author:
Funder
BRACE
Alzheimer's Research UK
Publisher
Elsevier BV
Subject
Cell Biology,Cellular and Molecular Neuroscience,Molecular Biology
Reference49 articles.
1. Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system;Abeliovich;Neuron,2000
2. Alpha-synuclein occurs physiologically as a helically folded tetramer that resists aggregation;Bartels;Nature,2011
3. Interaction of alpha-synuclein with divalent metal ions reveals key differences: a link between structure, binding specificity and fibrillation enhancement;Binolfi;J. Am. Chem. Soc.,2006
4. 3,4-dihydroxyphenylacetaldehyde: a potential target for neuroprotective therapy in Parkinson's disease;Burke;Curr. Drug Targets CNS Neurol. Disord.,2003
5. 3,4-Dihydroxyphenylacetaldehyde is the toxic dopamine metabolite in vivo: implications for Parkinson's disease pathogenesis;Burke;Brain Res.,2003
Cited by 19 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Alpha-synuclein affects certain iron transporters of BV2 microglia cell through its ferric reductase activity;Journal of Neurophysiology;2024-08-01
2. Driving factors of neuronal ferroptosis;Trends in Cell Biology;2024-07
3. Cell senescence induced by toxic interaction between α-synuclein and iron precedes nigral dopaminergic neuron loss in a mouse model of Parkinson’s disease;Acta Pharmacologica Sinica;2023-09-06
4. Brain Iron Metabolism, Redox Balance and Neurological Diseases;Antioxidants;2023-06-16
5. Dietary Trace Elements and the Pathogenesis of Neurodegenerative Diseases;Nutrients;2023-04-25
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3