The Tubulin-Binding Agent Combretastatin A-4-Phosphate Arrests Endothelial Cells in Mitosis and Induces Mitotic Cell Death

Author:

Kanthou Chryso,Greco Olga,Stratford Anna,Cook Ian,Knight Richard,Benzakour Omar,Tozer Gillian

Funder

Cancer Research UK

Publisher

Elsevier BV

Subject

Pathology and Forensic Medicine

Reference48 articles.

1. Tumour vasculature as a target for cancer therapy;Chaplin;Br J Cancer,1999

2. The tumour microcirculation as a target in cancer therapy: a clearer perspective;Denekamp;Eur J Clin Invest,1999

3. Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A4;Pettit;Experientia,1989

4. The biology of the combretastatins as tumour vascular targeting agents;Tozer;Int J Exp Pathol,2002

5. Combretastatin A-4 phosphate as a tumor vascular-targeting agent: early effects in tumors and normal tissues;Tozer;Cancer Res,1999

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