Moringa oleifera seed oil modulates redox imbalance and iNOS/NF-κB/caspase-3 signaling pathway to exert antioxidant, anti-inflammatory and antiapoptotic mechanisms against anticancer drug 5-fluorouracil-induced nephrotoxicity in rats

Author:

Famurewa A.C.,Asogwa N.T.,Aja P.M.,Akunna G.G.,Awoke J.N.,Ekeleme-Egedigwe C.A.,Maduagwuna E.K.,Folawiyo A.M.,Besong E.E.,Ekpono E.U.,Nwoha P.A.

Publisher

Elsevier BV

Subject

Plant Science

Reference56 articles.

1. Protective effect of Moringa oleifera oil against HgCl2-induced hepato and nephrotoxicity in rats;Abarikwu;J. Basic Clin. Physiol. Pharmacol.,2017

2. Oral administration of Moringa oleifera oil but not coconut oil prevents mercury-induced testicular toxicity in rats;Abarikwu;Andrologia,2017

3. The possible protective effect of ginger against intestinal damage induced by methotrexate in rats;Abd-allah;Med. J. Cairo Univ.,2013

4. Ameliorative effect of vitamin C against 5-fluorouracil-induced hepatotoxicity in mice: a light and electron microscope study;Abou-Zeid;J. Basic Appl. Zool.,2014

5. Protocatechuic acid ameliorates neurobehavioral deficits via suppression of oxidative damage, inflammation, caspase-3 and acetylcholinesterase activities in diabetic rats;Adedara;Food Chem. Toxicol.,2019

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