An interleukin 10 Receptor alpha (IL-10RA) variant with a compound heterozygote mutation shows normal IL-10 signaling activity
Author:
Funder
Ruijin Hospital
National Natural Science Foundation of China
Publisher
Elsevier BV
Subject
Cell Biology,Genetics (clinical),Molecular Biology,Biochemistry
Reference5 articles.
1. Interleukin 1β mediates intestinal inflammation in mice and patients with interleukin 10 Receptor deficiency;Shouval;Gastroenterology,2016
2. Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signaling;Koelink;Gut,2020
3. Phenotypic characterization of very early-onset inflammatory bowel disease with interleukin-10 signaling deficiency: based on a large cohort study;Zheng;Inflamm Bowel Dis,2019
4. Clinical and genetic spectrum of children with congenital diarrhea and enteropathy in China;Ye;Genet Med,2019
5. Valuable clinical indicators for identifying infantile-onset inflammatory bowel disease patients with monogenic diseases;Su;World J Gastroenterol,2021
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