Eco-friendly stability-indicating HPTLC micro-determination of the first FDA approved SARS-CoV-2 antiviral prodrug Remdesivir: Study of degradation kinetics and structural elucidation of the degradants using HPTLC-MS-Reference-Cited by-同舟云学术

Eco-friendly stability-indicating HPTLC micro-determination of the first FDA approved SARS-CoV-2 antiviral prodrug Remdesivir: Study of degradation kinetics and structural elucidation of the degradants using HPTLC-MS

Published:2022-10 Issue: Volume:29 Page:100744
ISSN:2352-5541
Container-title:Sustainable Chemistry and Pharmacy
language:en
Short-container-title:Sustainable Chemistry and Pharmacy

Author:

Abo-Gharam Amira H.,El-Kafrawy Dina S.

Funder

Alexandria University

Publisher

Elsevier BV

Subject

Management, Monitoring, Policy and Law,Pharmaceutical Science,Pollution,Environmental Chemistry

Reference43 articles.

1. Quantification of plasma remdesivir and its metabolite GS-441524 using liquid chromatography coupled to tandem mass spectrometry. Application to a Covid-19 treated patient;Alvarez;Clin. Chem. Lab. Med.,2020

2. Development and validation of a UHPLC-MS/MS method for quantification of the prodrug remdesivir and its metabolite GS-441524: a tool for clinical pharmacokinetics of SARS-CoV-2/COVID-19 and Ebola virus disease;Avataneo;J. Antimicrob. Chemother.,2020

3. A comparative study of HPLC and UV spectrophotometric methods for remdesivir quantification in pharmaceutical formulations;Bulduk;J. TAIBAH UNIV. SCI.,2021

4. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study;Chen;Lancet,2020

5. Remdesivir: a review of its discovery and development leading to emergency use authorization for treatment of COVID-19;Eastman;ACS Cent. Sci.,2020

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