Lack of CYP1A responsiveness in species inhabiting chronically contaminated habitats: Two varieties of resistance?

Author:

Brammell Ben F.,Price David J.,Birge Wesley J.,Elskus Adria A.

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Cell Biology,Toxicology,Physiology,Biochemistry,General Medicine

Reference56 articles.

1. Evidence for resistance to benzo(a)pyrene and 3,4,3′4′-tetrachlorobiphenyl in a chronically polluted Fundulus heteroclitus population;Arzuaga;Mar. Environ. Res.,2002

2. Polluted-site killifish (Fundulus heteroclitus) embryos are resistant to organic pollutant-mediated induction of CYP1A activity, reactive oxygen species, and heart deformities;Arzuaga;Environ. Toxicol. Chem.,2010

3. Acquired resistance to Ah receptor agonists in a population of Atlantic killifish (Fundulus heteroclitus) inhabiting a marine superfund site: in vivo and in vitro studies on the inducibility of xenobiotic metabolizing enzymes;Bello;Toxicol. Sci.,2001

4. Birge, W.J., Black, J.A., Bruser, D.M., Price, D.J., Short, T.M., Silberhorn, E.M., Zuiderveen, J.A., 1988. Occurrence, Transport and Fate of Contaminant in Kentucky Freshwater Systems-Green River Drainage. Final Report (MA-7021). Cabinet for Natural Resources and Environmental Protection. Frankfort, KY. 94 p.

5. Brammell, B.F., 2005. Characterization of pollutant response in teleosts with varying degrees of pollutant sensitivity In: Biology, vol. Ph.D. University of Kentucky Lexington, KY, p. 183

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