Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies

Author:

Goyon Alexandre,Excoffier Melissa,Janin-Bussat Marie-Claire,Bobaly Balazs,Fekete Szabolcs,Guillarme Davy,Beck Alain

Funder

Swiss National Science Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Biochemistry,General Medicine,Analytical Chemistry

Reference42 articles.

1. CDER therapeutic biologic products;FDA,2017

2. Antibodies to watch in 2017;Reichert;MAbs,2017

3. Strategies and challenges for the next generation of therapeutic antibodies;Beck;Nat. Rev. Immunol.,2010

4. Chromatographic electrophoretic, and mass spectrometric methods for the analytical characterization of protein biopharmaceuticals;Fekete;Anal. Chem.,2016

5. Bloomberg. Available at https://www.bloomberg.com/news/articles/2016-07-12/amgen-moves-closer-to-selling-competitor-for-abbvie-s-humira. Accessed 2 July, 2017.

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