Reconstruction of the pulmonary artery by a novel biodegradable conduit engineered with perinatal stem cell-derived vascular smooth muscle cells enables physiological vascular growth in a large animal model of congenital heart disease

Author:

Ghorbel Mohamed T.,Jia Huidong,Swim Megan M.,Iacobazzi Dominga,Albertario Ambra,Zebele Carlo,Holopherne-Doran Delphine,Hollander Anthony,Madeddu Paolo,Caputo Massimo

Funder

Sir Jules Thorn Charitable Trust

British Heart Foundation

Medical Research Council

Publisher

Elsevier BV

Subject

Mechanics of Materials,Biomaterials,Biophysics,Ceramics and Composites,Bioengineering

Reference34 articles.

1. Congenital heart disease: causes, diagnosis, symptoms, and treatments;Sun;Cell Biochem. Biophys.,2015

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3. Tissue engineering of heart valves using decellularized xenogeneic or polymeric starter matrices;Schmidt;Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci.,2007

4. Decellularization protocols of porcine heart valves differ importantly in efficiency of cell removal and susceptibility of the matrix to recellularization with human vascular cells;Rieder;J. Thorac. Cardiovasc. Surg.,2004

5. Consequences of ineffective decellularization of biologic scaffolds on the host response;Keane;Biomaterials,2012

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