A defined xeno-free and feeder-free culture system for the derivation, expansion and direct differentiation of transgene-free patient-specific induced pluripotent stem cells

Author:

Lu Hong Fang,Chai Chou,Lim Tze Chiun,Leong Meng Fatt,Lim Jia Kai,Gao Shujun,Lim Kah Leong,Wan Andrew C.A.

Funder

Institute of Bioengineering and Nanotechnology

Singapore National Research Foundation – Competitive Research Program grant

National Medical Research Council NIG grant

Publisher

Elsevier BV

Subject

Mechanics of Materials,Biomaterials,Biophysics,Ceramics and Composites,Bioengineering

Reference48 articles.

1. Generation of isogenic pluripotent stem cells;Byrne;Hum Mol Genet,2008

2. Nuclear reprogramming and the current challenges in advancing personalized pluripotent stem cell-based therapies;Byrne;Gene Ther Reg,2013

3. Induced pluripotent stem cells–opportunities for disease modelling and drug discovery;Grskovic;Nat Rev Drug Discov,2011

4. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin;Hanna;Science,2007

5. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome;Carvajal-Vergara;Nature,2010

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