Feasibility and safety of treating non-unions in tibia, femur and humerus with autologous, expanded, bone marrow-derived mesenchymal stromal cells associated with biphasic calcium phosphate biomaterials in a multicentric, non-comparative trial

Author:

Gómez-Barrena Enrique,Rosset Philippe,Gebhard Florian,Hernigou Philippe,Baldini Nicola,Rouard Helène,Sensebé Luc,Gonzalo-Daganzo Rosa M.,Giordano Rosaria,Padilla-Eguiluz Norma,García-Rey Eduardo,Cordero-Ampuero José,Rubio-Suárez Juan Carlos,Stanovici Julien,Ehrnthaller Christian,Huber-Lang Markus,Flouzat-Lachaniette Charles Henri,Chevallier Nathalie,Donati Davide Maria,Ciapetti Gabriela,Fleury Sandrine,Fernandez Manuel-Nicolás,Cabrera José-Rafael,Avendaño-Solá Cristina,Montemurro Tiziana,Panaitescu Carmen,Veronesi Elena,Rojewski Markus Thomas,Lotfi Ramin,Dominici Massimo,Schrezenmeier Hubert,Layrolle Pierre

Funder

European Union's Seventh Framework Programme

REBORNE

Publisher

Elsevier BV

Subject

Mechanics of Materials,Biomaterials,Biophysics,Ceramics and Composites,Bioengineering

Reference21 articles.

1. Bone fracture healing: cell therapy in delayed unions and nonunions;Gomez-Barrena;Bone,2015

2. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions;Friedlaender;J Bone Joint Surg Am.,2001

3. Bone regeneration and stem cells;Arvidson;J. Cell Mol. Med.,2011

4. Morbidity of graft harvesting versus bone marrow aspiration in cell regenerative therapy;Hernigou;Int. Orthop.,2014

5. Bone morphogenetic protein (BMP) for fracture healing in adults;Garrison;Cochrane Database Syst. Rev.,2010

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