The dichotomy of the Insulin-like growth factor 1 receptor: RTK and GPCR: friend or foe for cancer treatment?

Author:

Crudden Caitrin,Ilic Marina,Suleymanova Naida,Worrall Claire,Girnita Ada,Girnita LeonardORCID

Funder

Swedish Research Council

Swedish Cancer Society

Children Cancer Society

Crown Princess Margareta's Foundation for the Visually Impaired

Welander Finsen Foundation

King Gustaf V Jubilee Foundation

Stockholm Cancer Society

Stockholm County

Karolinska Institutet

Publisher

Elsevier BV

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Reference158 articles.

1. Growth factors and cancer;Aaronson;Science,1991

2. Structure and function of the type 1 insulin-like growth factor receptor;Adams;Cell. Mol. Life Sci.,2000

3. Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma;Ahlen;Clin. Cancer Res.,2005

4. Ubiquitin ligase parkin promotes Mdm2-arrestin interaction but inhibits arrestin ubiquitination;Ahmed;Biochemistry,2011

5. Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2;Ahn;J. Biol. Chem.,2004

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