An evaluation of the roles of mammalian cell mutation assays in the testing of chemical genotoxicity

Author:

Li A.P.,Aaron C.S.,Auletta A.E.,Dearfield K.L.,Riddle J.C.,Slesinski R.S.,Stankowski L.F.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference45 articles.

1. Comparison of the AS52XPT and the CHOHPRT assays: Evaluation of six drug candidates;Aaron;Mutat. Res.,1989

2. Comparative mutagenicity testing of a drug candidate: U-73,975, a potent AT-binding agent, is also extremely potent in inducing genetic changes in a variety of system;Aaron;Environ. Mol. Mutagen.,1988

3. Comparative mutagenicity testing of a drug candidate, U-48753E: Mechanism of induction of gene mutations in mammalian cells and quantitation of potential hazard;Aaron;Mutat. Res.,1989

4. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenicity test;Ames;Mutat. Res.,1975

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