17-β-Hydroxysteroid dehydrogenase type 1: computational design of active site inhibitors targeted to the Rossmann fold

Author:

Brown William M,Metzger Louis E,Barlow Jeremy P,Hunsaker Lucy A,Deck Lorraine M,Royer Robert E,Vander Jagt David L

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference29 articles.

1. Regulation of estrogen action: role of 17 beta-hydroxysteroid dehydrogenases;Peltoketo;Vit. Horm.,1999

2. Molecular endocrinology of hydroxysteroid dehydrogenases;Penning;Endocr. Rev.,1997

3. Overview of a rational approach to design type I 17beta-hydroxysteroid dehydrogenase inhibitors without estrogenic activity: chemical synthesis and biological evaluation;Tremblay;J. Steroid Biochem. Mol. Biol.,1998

4. Intracrinology;Labrie;Mol. Cell. Endocrinol.,1991

5. Short-chain dehydrogenases/reductases (SDR);Jornvall;Biochemistry,1995

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