Mechanisms of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (dacarbazine) cytotoxicity toward chinese hamster ovary cells in vitro are dictated by incubation conditions

Author:

Saunders Priscilla P.,DeChang Wang,Chao Lian-Yu

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference20 articles.

1. N-Demethylation of the anti neoplastic agent 4(5)-(3,3-dimethyl-1-triazeno)imidazole-5(4)-carboxamide by rats and man;Skibba;Cancer Res.,1970

2. Mechanism of action of 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide in mammalian cells in culture;Gerulath;Biochem. Pharmacol.,1972

3. Metabolism of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide in human and animal tumor tissue;Mizuno;Cancer Chemother. Rep.,1972

4. Effects of 5-(3-methyl-triazeno)imidazole-4-carboxamide (NSC 45388);Mizuno;Biochem. Pharmacol.,1975

5. Effects of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide and its metabolites on Novikoff Hepatoma cells;Beal;Cancer Res.,1976

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