Zomepirac acyl glucuronide covalently modifies tubulin in vitro and in vivo and inhibits its assembly in an in vitro system
Author:
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference29 articles.
1. Properties of acyl glucuronides: Implications for studies of the pharmacokinetics and metabolism of acidic drugs;Faed;Drug Metab. Rev.,1984
2. Acyl glucuronides revisited: Is the glucuronidation process a toxification as well as a detoxification mechanism?;Spahn-Langguth;Drug Metab. Rev.,1992
3. Acyl glucuronide conjugates: reactive metabolites of non-steroidal anti-inflammatory drugs;Dickinson;Proc. Western Pharmacol. Soc.,1993
4. Acyl glucuronides as chemically reactive intermediates;Fenselau;Hdbk. Exp. Pharmacol.,1994
5. Evidence for covalent binding of acyl glucuronides to serum albumin via an imine mechanism as revealed by tandem mass spectrometry;Ding;Proc. Natl. Acad. Sci. USA,1993
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