An evaluation of the cytochrome P450 induction potential of pantoprazole in primary human hepatocytes

Author:

Masubuchi Noriko,Li Albert P,Okazaki Osamu

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference24 articles.

1. Effect of repeated oral administration of BY 1023/SK&F96022–a new substituted benzimidazole derivative-on pentagastrin-stimulated gastric acid secretion and pharmacokinetics in man;Simon;Aliment. Pharmacol. Ther.,1990

2. Effects of benzimidazole derivatives on cytochrome P450 1A1 expression in a human hepatoma cell line;Krusekopf;Xenobiotica,1997

3. Effects of pantoprazole on xenobiotic metabolizing enzymes in rat liver microsomes: a comparison with other proton pump inhibitors;Masubuchi;Drug. Metab. Disp.,1997

4. A.P. Li, Primary hepatocyte culture as an in vitro toxicological system, in: S. Gad (Ed.), In Vitro Toxicology, Raven Press, New York, 1994, pp. 195–220.

5. Comparative metabolism of SC-42867 and SC-51089, two PGE2 antagonists, in rat and human hepatocyte cultures;Lee;Xenobiotica,1994

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