anti-Aldol reactions of lactate-derived ketones. Application to the synthesis of (−)-tetrahydrolipstatin
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference23 articles.
1. Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. I. Producing organism, fermentation, isolation and biological activity.
2. Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. II. Chemistry and structure elucidation.
3. Inhibition of pancreatic lipase in vitro by the covalent inhibitor tetrahydrolipstatin
4. Mode of action of tetrahydrolipstatin: a derivative of the naturally occurring lipase inhibitor lipstatin
5. Syntheses of Tetrahydrolipstatin and Absolute Configuration of Tetrahydrolipstatin and Lipstatin
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1. Substrate-Controlled Aldol Reactions from Chiral α-Hydroxy Ketones;Synthesis;2016-10-12
2. The Asymmetric Synthesis of Tetrahydrolipstatin;Asian Journal of Organic Chemistry;2015-08-31
3. Asymmetric syntheses of the lactone core of tetrahydrolipstatin and tetrahydroesterastin and of the oriental hornet Vespa Orientalis pheromone;Russian Journal of Organic Chemistry;2015-06
4. Total Synthesis of Tetrahydrolipstatin and Stereoisomers via a Highly Regio- and Diastereoselective Carbonylation of Epoxyhomoallylic Alcohols;Journal of the American Chemical Society;2014-07-18
5. An Adventurous Synthetic Journey with MNBA from Its Reaction Chemistry to the Total Synthesis of Natural Products;Bulletin of the Chemical Society of Japan;2014-02-15
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