A cobaloxime-mediated synthesis of the ras farnesyl-protein transferase inhibitor chaetomellic acid A
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference6 articles.
1. Ras C-terminal processing enzymes—New drug targets?
2. Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.
3. Isolation and structure of chaetomellic acids A and B from Chaetomella acutiseta: farnesyl pyrophosphate mimic inhibitors of ras farnesyl-protein transferase
4. Chaetomella acutiseta produces chaetomellic acids A and B which are reversible inhibitors of farnesyl-protien transferase
5. Synthesis of chaetomellic acid A: A potent inhibitor of Ras farnesyl-protein transferase
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