Efficient synthesis of (±)-N-BOC-exo-2-(methoxycarbonyl)-7-Azabicyclo[2.2.1]heptane, a versatile intermediate for the synthesis of epibatidine and epiboxidine-Reference-Cited by-同舟云学术

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Efficient synthesis of (±)-N-BOC-exo-2-(methoxycarbonyl)-7-Azabicyclo[2.2.1]heptane, a versatile intermediate for the synthesis of epibatidine and epiboxidine

Published:1997-09 Issue:39 Volume:38 Page:6829-6830
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Singh Satendra,Basmadjian Garo P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference12 articles.

1. Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an Ecuadoran poison frog

2. Epibatidine is a nicotinic analgesic

3. Chemistry of 7-Azabicyclo[2.2.1]hepta-2,5-dienes, 7-Azabicyclo[2.2.1]hept-2-enes, and 7-Azabicyclo[2.2.1]heptanes

4. Synthesis and nicotinic activity of epiboxidine: an isoxazole analogue of epibatidine

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5. Water-Stable Helical Structure of Tertiary Amides of Bicyclic β-Amino Acid Bearing 7-Azabicyclo[2.2.1]heptane. Full Control of Amide Cis−Trans Equilibrium by Bridgehead Substitution;Journal of the American Chemical Society;2010-09-30

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