Process development of potassium channel opener, TCV-295, based on convenient ring formation of 2H-1,3-benzoxazine and selective N-oxidation of the pyridyl moiety-Reference-Cited by-同舟云学术

Process development of potassium channel opener, TCV-295, based on convenient ring formation of 2H-1,3-benzoxazine and selective N-oxidation of the pyridyl moiety

Published:2001-08 Issue:35 Volume:57 Page:7501-7506
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Mizufune Hideya,Irie Hiroyuki,Katsube Susumu,Okada Tadataka,Mizuno Yukio,Arita Miichiro

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference16 articles.

1. Synthesis and Biological Activity of Novel 1,3-Benzoxazine Derivatives as K+ Channel Openers.

2. Antihypertensive and Cardiovascular Effects of a New Potassium Channel Opener, TCV-295, in Rats and Dogs

3. Baumgarth, M., Gericke, R., Bergmann, R., De Peyer, J., Ingeborg, L. DE3840011(CA114(17):164256m).

4. Englert, H. C., Mania, D., Lintz, W. DE4010488(CA116(5):41463k).

5. Melzig, M. WO90-03379(CA114(5):42796s).

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