Total synthesis of a pepstatin analog incorporating two trifluoromethyl hydroxymethylene isosteres (Tfm-GABOB) and evaluation of Tfm-GABOB containing peptides as inhibitors of HIV-1 protease and MMP-9-Reference-Cited by-同舟云学术

Total synthesis of a pepstatin analog incorporating two trifluoromethyl hydroxymethylene isosteres (Tfm-GABOB) and evaluation of Tfm-GABOB containing peptides as inhibitors of HIV-1 protease and MMP-9

Published:2001-07 Issue:30 Volume:57 Page:6511-6522
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Pesenti Cristina,Arnone Alberto,Bellosta Stefano,Bravo Pierfrancesco,Canavesi Monica,Corradi Eleonora,Frigerio Massimo,Meille Stefano V,Monetti Mara,Panzeri Walter,Viani Fiorenza,Venturini Romina,Zanda Matteo

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference49 articles.

1. PEPSTATIN, A NEW PEPSIN INHIBITOR PRODUCED BY AGTINOMYGETES

2. Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design

3. Pepstatin-derived inhibitors of aspartic proteinases. A close look at an apparent transition-state analog inhibitor

4. Simplified Pepstatins: Synthesis and Evaluation of N-Terminally Modified Analogues

5. Novel renin inhibitors containing the amino acid statine

Cited by 36 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Enantioselective addition of thiols to trifluoromethyl ketimines: synthesis of N,S-ketals;Organic & Biomolecular Chemistry;2020

2. Formylation of Fluoroalkyl Imines through Visible-Light-Enabled H-Atom Transfer Catalysis: Access to Fluorinated α-Amino Aldehydes;Organic Letters;2019-03-22

3. An enantioselective aza-Henry reaction of trifluoromethyl ketimines catalyzed by phase-transfer catalysts;Organic Chemistry Frontiers;2019

4. Direct Catalytic Asymmetric Synthesis of Trifluoromethylated γ-Amino Esters/Lactones via Umpolung Strategy;The Journal of Organic Chemistry;2018-12-13

5. Catalytic Asymmetric Synthesis of Trifluoromethylated γ-Amino Acids through the Umpolung Addition of Trifluoromethyl Imines to Carboxylic Acid Derivatives;Angewandte Chemie International Edition;2018-01-18