Stereoselective conversion of 2 H -1,4-oxazin-2-ones into 2,5,5-substituted piperidine-2-carboxamides and 2-methanamines and related octahydro-2 H -pyrido[1,2- a ]pyrazines, potential substance P antagonists-Reference-Cited by-同舟云学术

Stereoselective conversion of 2 H -1,4-oxazin-2-ones into 2,5,5-substituted piperidine-2-carboxamides and 2-methanamines and related octahydro-2 H -pyrido[1,2- a ]pyrazines, potential substance P antagonists

Published:2001-10 Issue:43 Volume:57 Page:8971-8981
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Rogiers Joeri,Wu Xiujuan,Toppet Suzanne,Compernolle Frans,Hoornaert Georges J

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference23 articles.

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4. Stereoselective Transformation of 2H-1,4-Oxazin-2-ones into 2,(2),5,5-Tri- and Tetrasubstituted Analogues of cis-5-Hydroxy-2-piperidinemethanol and cis-5-Hydroxy-6-oxo-2-piperidinecarboxylic Acid

5. Synthesis of 3,5-dihalogeno-2H-1,4-oxazin-2-ones from cyanohydrines

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1. A Merged Aldol Condensation, Alkene Isomerization, Cycloaddition/Cycloreversion Sequence Employing Oxazinone Intermediates for the Synthesis of Substituted Pyridines;Synlett;2017-02-23

2. [4 + 2] Cycloaddition of in Situ Generated 1,2-Diaza-1,3-dienes with Simple Olefins: Facile Approaches to Tetrahydropyridazines;Organic Letters;2015-03-04

3. ChemInform Abstract: Stereoselective Conversion of 2H-1,4-Oxazin-2-ones into 2,5,5-Substituted Piperidine-2-carboxamides and 2-Methanamines and Related Octahydro-2H-pyrido[1,2-a]pyrazines, Potential Substance P Antagonists.;ChemInform;2010-05-22

4. Bicyclic 6-6 Systems with One Bridgehead (Ring Junction) Nitrogen Atom: One Extra Heteroatom 1:0;Comprehensive Heterocyclic Chemistry III;2008

5. An unusual bicyclic aziridine, 1-azabicyclo[4.1.0]heptan-2-one, and its reaction with nucleophiles;Tetrahedron;2003-02