Remarkable enhancement of binding affinity of Heterocycle-modified DNA to DNA and RNA. Synthesis, characterization and biophysical evaluation of N2-imidazolylpropylguanine and N2-imidazolylpropyl-2-aminoadenine modified oligonucleotides-Reference-Cited by-同舟云学术

Remarkable enhancement of binding affinity of Heterocycle-modified DNA to DNA and RNA. Synthesis, characterization and biophysical evaluation of N2-imidazolylpropylguanine and N2-imidazolylpropyl-2-aminoadenine modified oligonucleotides

Published:1994-01 Issue:2 Volume:35 Page:215-218
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Ramasamy Kanda S.,Zounes Maryann,Gonzalez Carolyn,Freier Susan M.,Lesnik Elena A.,Cummins Lendell L.,Griffey Richard H.,Monia Brett P.,Dan Cook P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference21 articles.

1. Antisense oligonucleotides: a new therapeutic principle

2. Role of RNase H in hybrid-arrested translation by antisense oligonucleotides.

3. Pathways of Degradation and Mechanism of Action of Antisense Oligonucleotides inXenopus laevisEmbryos

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