Inhibition of the tissue factor/factor VIIa complex — Lead optimisation using combinatorial chemistry
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference20 articles.
1. Initiation and regulation of tissue factor-dependent blood coagulation.
2. Kinetics of Human Factor VII Activation
3. Factor VII autoactivation proceeds via interaction of distinct protease-cofactor and zymogen-cofactor complexes. Implications of a two-dimensional enzyme kinetic mechanism.
4. The contributions of Ca2+, phospholipids and tissue-factor apoprotein to the activation of human blood-coagulation factor X by activated factor VII
5. Antithrombotic Benefits and Hemorrhagic Risks of Direct Thrombin Antagonists
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