Evaluation of asymmetric Diels–Alder approaches for the synthesis of the cyclohexene subunit of CP-225,917 and CP-263,114

Author:

Armstrong Alan,Davies Nicholas G.M.,Martin Nathaniel G.,Rutherford Alistair P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference26 articles.

1. CP-225,917 and CP-263,114, Novel Ras Farnesylation Inhibitors from an Unidentified Fungus. I. Taxonomy, Fermentation, Isolation, and Biochemical Properties.

2. CP-225,917 and CP-263,114:  Novel Ras Farnesylation Inhibitors from an Unidentified Fungus. 2. Structure Elucidation

3. For reviews, see: (a) Hepworth, D. Chem. Ind. 2000, 59–65;

4. (b) Starr, J. T.; Carreira, E. M. Angew. Chem., Int. Ed. 2000, 39, 1415–1421.

5. For total syntheses, see: (a) Nicolaou, K. C.; Baran, P. S. Angew. Chem., Int. Ed. 2002, 41, 2679–2720; Nicolaou, K. C.; Jung, J.; Yoon, W. H.; Fong, K. C.; Choi, H.-S.; He, Y.; Zhong, Y.-L.; Baran, P. S. J. Am. Chem. Soc. 2002, 124, 2183–2189; Nicolaou, K. C.; Baran, P. S.; Zhong, Y.-L.; Fong, K. C.; Choi, H.-S. J. Am. Chem. Soc. 2002, 124, 2190–2201; Nicolaou, K. C.; Zhong, Y.-L.; Baran, P. S.; Jung, J.; Choi, H.-S.; Yoon, W. H. J. Am. Chem. Soc. 2002, 124, 2202–2211;

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