Asymmetric synthesis of enantiomerically pure (−)-(1′R,4′R)-dioxolane-thymine and its anti-HIV activity.-Reference-Cited by-同舟云学术

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Asymmetric synthesis of enantiomerically pure (−)-(1′R,4′R)-dioxolane-thymine and its anti-HIV activity.

Published:1991-07 Issue:31 Volume:32 Page:3791-3794
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Chu Chung K.,Ahn Soon K.,Kim H.O.,Beach J.Warren,Alves Antonio J.,Jeong Lak S.,Islam Qamrul,Roey Patrick Van,Schinazi Raymond F.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference20 articles.

1. Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

2. Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells

3. Phosphorylation of 3'-azido-2',3'-dideoxyuridine and preferential inhibition of human and simian immunodeficiency virus reverse transcriptases by its 5'-triphosphate

4. In Vivo Activity Against HIV and Favorable Toxicity Profile of 2′,3′-Dideoxyinosine

5. Antiviral activity of 2′,3′-dideoxycytidin-2′-ene (2′,3′-dideoxy-2′,3′-didehydrocytidine) against human immunodeficiency virus in vitro

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1. In Vitro and In Silico Studies of Human Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) Inhibition by Stereoisomeric Forms of Lipophilic Nucleosides: The Role of Carbohydrate Stereochemistry in Ligand-Enzyme Interactions;Molecules;2022-04-09

2. Synthesis and antimicrobial screening of novel 1,3-dioxolanes linked to N-5 of 5H-[1,2,4]triazino[5,6-b]indole-3-thiol;Journal of the Serbian Chemical Society;2019

3. Construction of an Isonucleoside on a 2,6-Dioxobicyclo[3.2.0]-heptane Skeleton;Molecules;2015-03-12

4. Stereoselective Methods in the Synthesis of Bioactive Oxathiolane and Dioxolane Nucleosides;Chemical Synthesis of Nucleoside Analogues;2013-02-15

5. Scaleable processes for the synthesis of (−)-β-d-2,6-diaminopurine dioxolane (Amdoxovir, DAPD) and (−)-β-d-2-aminopurine dioxolane (APD);Tetrahedron;2012-07

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