Application of the grubbs ring-closing metathesis for the construction of a macrocyclic ansa-bridge. Synthesis of the tricyclic core of roseophilin
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference29 articles.
1. Structure of a new antibiotic, roseophilin
2. Synthesis of various model compounds for the conjugated heterocyclic ring system of antibiotic roseophilin
3. Synthesis of beta-substituted cyclopentenones via carbon alkylation of metalated gamma-methoxycyclopentenyl phenylsulfonyl anion
4. Phosphazene base P2-Et mediated isomerization of vinyl sulfones to allyl sulfones
5. Conversion of δ-(sulfonyl)amino-α-epoxy ketones to bicyclic ketopyrroles via intramolecular conjugate-addition to azoene intermediates. Synthesis of the bicyclic ketopyrrole core of the 1-azafulvene roseophllin
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3. Mild Friedel–Crafts Reactions Enable a Robust Synthesis of Roseophilin;Organic Letters;2019-04-22
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