A total synthesis of toddaquinoline exposes a dual role for cobalt in radical additions to pyridines
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference9 articles.
1. Harrowven, D. C.; Nunn, M. I. T. Tetrahedron Lett. 1998, 39, 5875.
2. Toddaquinoline was isolated from the root bark of Toddalia asiatica., see: (a) Chen, I. S.; Tsai, I. L.; Wu, S. J.; Sheen, W. S.; Ishikawa, T.; Ishii, H. Phytochem. 1993, 34, 1449; (b) Chen, I. S.; Wu, S. J.; Tsai, I. L. J. Nat. Prod. 1994, 57, 1206.
3. For recent examples of intramolecular radical additions to pyridines, see: (a) de Mata, M. L. E. N.; Motherwell, W. B.; Ujjainwalla, F. Tetrahedron Lett. 1997, 38, 141;
4. (b) de Mata, M. L. E. N.; Motherwell, W. B.; Ujjainwalla, F. Tetrahedron Lett. 1997, 38, 137;
5. (c) Murphy, J. A.; Sherburn, M. S. Tetrahedron 1991, 47, 4077.
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