Dearomatising cyclisation of lithiated 1-naphthamides with a phenylglycinol-derived chiral auxiliary: asymmetric synthesis of an arylkainoid and a kainoid-like pyroglutamate
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference32 articles.
1. Synthesis of a potent (±)-4-(2-hydroxyphenyl) analogue of the acromelic acids by dearomatising cyclisation of a lithiated N-p-methoxybenzyl-4-methoxy-1-naphthamide
2. Simple analogs of acromelic acid, which are highly active agonists of kainate type neuroexcitant
3. Anionic cyclisations of an N-benzyl naphthamide: a route to benzo[e]isoindolones
4. Pyrrolidinones derived from (S )-pyroglutamic acid. Part 1. Conformationally constrained glutamate
5. Pyrrolidinones derived from (S )-pyroglutamic acid. Part 2. Conformationally constrained kainoid analogues
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