Synthesis of [4-2H2]-, (4R)[4-2H1]- and (4S)[4-2H1]- 4-(methylnitrosamino)-1-(3'-pyridyl)-1-butanone, c-4 deuteriated isotopomers of the procarcinogen nnk-Reference-Cited by-同舟云学术

Synthesis of [4-2H2]-, (4R)[4-2H1]- and (4S)[4-2H1]- 4-(methylnitrosamino)-1-(3'-pyridyl)-1-butanone, c-4 deuteriated isotopomers of the procarcinogen nnk

Published:1990-01 Issue:5 Volume:46 Page:1733-1744
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Pathak Tanmaya,Thomas Noel F.,Akhtar Mahmoud,Gani David

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference12 articles.

1. Chemical studies on tobacco smoke. 52. Reaction of nicotine and sodium nitrite: formation of nitrosamines and fragmentation of the pyrrolidine ring

2. Metabolism of tobacco-specific N-nitrosamines by cultured human tissues.

3. Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke

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