Molecular mechanics and 1H NMR conformational study of 3,8-diazabicyclo[3,2,1] octanes and related cis-2,6-dimethylpiperazines active on opioid receptors-Reference-Cited by-同舟云学术

Molecular mechanics and 1H NMR conformational study of 3,8-diazabicyclo[3,2,1] octanes and related cis-2,6-dimethylpiperazines active on opioid receptors

Published:1992-01 Issue:1 Volume:48 Page:159-166
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Toma Lucio,Cignarella Giorgio,Barlocco Daniela,Ronchetti Fiamma

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference7 articles.

1. Bicyclic Homologs of Piperazine. VI.1 Synthesis and Analgesic Activity of 3-Substituted 8-Propionyl-3,8-diazabicyclo[3.2.1]octanes

2. 2,6-Dialkylpiperazines. IV. 1-Propionyl-4-substituted cis-2,6-dimethylpiperazines structurally related to the analgetic 8-acyl-3,8-diazabicyclo[3.2.1] octanes

3. Interaction of 3,8-diazabicyclo (3.2.1) octanes with mu and delta opioid receptors

4. Falter, W., personal communication.

5. A molecular mechanics study of amide conformations

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