1. For examples of the use of silyl linkers in solid-phase synthesis see: (a) Chan, T. H.; Huang, W. Q. Chem. Commun. 1985, 909–911; (b) Hu, Y.; Porco, J., Jr.; Labadie, J. W.; Gooding, O. W.; Trost, B. M. J. Org. Chem. 1998, 63, 4518–4521; (c) Smith, E. M. Tetrahedron Lett. 1999, 40, 3285–3288; (d) Doi, T.; Sugiki, M; Yamada, H.; Takahashi, T.; Porco, J., Jr. Tetrahedron Lett. 1999, 40, 2141–2144; (e) Hu, Y.; Porco, J., Jr. Tetrahedron Lett. 1999, 40, 3289–3292; (f) Stranix, B. R.; Liu, H. Q.; Darling, G. D. J. Org. Chem. 1997, 62, 6183–6186; (g) Newlander, K. A.; Chenera, B.; Veber, D. F.; Yim, N. C. F.; Moore, M. L. J. Org. Chem. 1997, 62, 6726–6732; (h) Brown, S. D.; Armstrong, R. W. J. Org. Chem. 1997, 62, 7076–7077; (i) Thompson, L. A.; Moore, F. L.; Moon, Y. C.; Ellmann, J. A. J. Org. Chem. 1998, 63, 2066–2067; (j) Wang, B.; Chen, L.; Kim, K., Tetrahedron Lett. 2001, 42, 1463–1466. For general reviews on linkers, see: (k) Brown, R. C. D. Recent developments in solid-phase organic chemistry, J. Chem. Soc., Perkin Trans. 1 1998, 3293–3320; (l) Guillier, F.; Orain, D.; Bradley, M. Chem. Rev. 2000, 100, 2091–2157.
2. For application of silyl linkers in traceless cleavage, see: (a) Plunkett, M. J.; Ellmann, J. A. J. Org. Chem. 1995, 60, 6006–6007;
3. (b) Plunkett, M. J.; Ellmann, J. A. J. Org. Chem. 1997, 62, 2885–2893;
4. (c) Woolard, F. X.; Paetsch, J.; Ellmann, J. A. J. Org. Chem. 1997, 62, 6102–6103;
5. (d) Lee, Y.; Silverman, R. B. Org. Lett. 2000, 3, 303–306;