Application of organolithium and related reagents in synthesis. Part 9. Synthesis and metallation of 4-chloropicolin- and 2-chloroisonicotinanilides. A useful method for preparation of 2,3,4-trisubstituted pyridines-Reference-Cited by-同舟云学术

Application of organolithium and related reagents in synthesis. Part 9. Synthesis and metallation of 4-chloropicolin- and 2-chloroisonicotinanilides. A useful method for preparation of 2,3,4-trisubstituted pyridines

Published:1991-01 Issue:9 Volume:47 Page:1697-1706
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Epsztajn Jan,Bieniek Adam,Kowalska Justyna A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference32 articles.

1. Oxazolines as activating groups in aromatic substitution. Regioselective metallation of the 3-position in pyridine.

2. Oxazolines as Activating Groups in Aromatic Substitution. Selective Metalation or Addition to the 4-Position of Pyridine. A New Synthesis of 1,4-Dihydropyridines

3. Tandem directed metalation reactions. Short syntheses of polycyclic aromatic hydrocarbons and ellipticine alkaloids

4. Reactions of the N,N-dialkylpyridylcarboxylic amides with lithium amides. Regioselective lithiation of N,N-diisopropylpyridylcarboxylic amides, a useful method for synthesis of 2,3- and 3,4-disubstituted pyridines

5. 3-Lithiated Pyridines and their Reactions with Electrophiles

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4. Achievement of regioselectivity in transition metal-catalyzed direct C–H (hetero)arylation reactions of heteroarenes with one heteroatom through the use of removable protecting/blocking substituents or traceless directing groups;Tetrahedron;2016-04

5. Directed Lithiation and Substitution of Pyridine Derivatives;HETEROCYCLES;2015