Synthesis of the α-Mannosidase inhibitors swainsonine [(1S, 2R, 8R, 8aR)-1,2,8-trihydroxyoctahydroindolizine] and 1,4-dideoxy-1,4-imino-d-mannitol from mannose-Reference-Cited by-同舟云学术

Synthesis of the α-Mannosidase inhibitors swainsonine [(1S, 2R, 8R, 8aR)-1,2,8-trihydroxyoctahydroindolizine] and 1,4-dideoxy-1,4-imino-d-mannitol from mannose

Published:1987-01 Issue:13 Volume:43 Page:3083-3093
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Bashyal Bharat P.,Fleet George W.J.,Gough Max J.,Smith Paul W.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference27 articles.

1. A Spectroscopic Investigation of Swainsonine: An α-Mannosidase Inhibitor Isolated from Swainsona canescens

2. (1S,2R,8R,8aR)-1,2,8-trihydroxyoctahydroindolizine (swainsonine), an α-mannosidase inhibitor from Rhizoctonia leguminicola

3. Studies of an immunomodulator, swainsonine. I. Enhancement of immune response by swainsonine in vitro.

4. Identification of swainsonine as a probable contributory mycotoxin in moldy forage mycotoxicoses

5. The biological activity of polyhydroxyalkaloids from plants

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