Nucleosides and nucleotides. 116. Convenient syntheses of 3-deazaadenosine, 3-deazaguanosine, and 3-deazainosine via ring closure of 5-ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide or -carbonitrile-Reference-Cited by-同舟云学术

Nucleosides and nucleotides. 116. Convenient syntheses of 3-deazaadenosine, 3-deazaguanosine, and 3-deazainosine via ring closure of 5-ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide or -carbonitrile

Published:1993-01 Issue:3 Volume:49 Page:557-570
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Minakawa Noriaki,Matsuda Akira

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference23 articles.

1. Perturbation of biochemical transmethylations by 3-deazaadenosine in vivo

2. 3-Deazaadenosine, an inhibitor of adenosylhomocysteine hydrolase, inhibits reproduction of rous sarcoma virus and transformation of chick embryo cells

3. Adenosylhomocysteine hydrolase inhibitors: Synthesis of 5′-deoxy-5′-(isobutylthio)-3-deazaadenosine and its effect on Rous sarcoma virus and Gross murine leukemia virus

4. Plasmodium falciparum: Antimalarial activity in culture of sinefungin and other methylation inhibitors

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