A general route to “carba” peptide bond replacements: Unequivocal synthesis of Boc--Phe-ψ(CH2-CH2)--Ala-OH and Boc--Phe-ψ(CH2-CH2)--Ala-OH.
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference7 articles.
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1. Access to C-protected β-amino-aldehydes via transacetalization of 6-alcoxy tetrahydrooxazinones and use for pseudo-peptide synthesis;Tetrahedron;2012-03
2. ChemInform Abstract: A General Route to “Carba” Peptide Bond Replacements: Unequivocal Synthesis of Boc-L-Phe-ψ(CH2-CH2)-L-Ala-OH and Boc-L-Phe-ψ(CH2- CH2)-D-Ala-OH.;ChemInform;2010-08-22
3. ChiralN-Phosphonylimine Chemistry: Asymmetric Synthesis ofN-Phosphonyl β-Amino Weinreb Amides;European Journal of Organic Chemistry;2009-02
4. Biological activity and three-dimensional structure of an agonist analog of bombesin;The Journal of Peptide Research;2009-01-12
5. “Carba” peptide bond surrogates Different approaches to Gly-Ψ(CH2-CH2)-d,l-Xaa pseudo-dipeptide units;International Journal of Peptide and Protein Research;2009-01-12
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