A novel synthesis of a key intermediate for diltiazem-Reference-Cited by-同舟云学术

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A novel synthesis of a key intermediate for diltiazem

Published:2001-11 Issue:46 Volume:42 Page:8201-8205
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Seki Masahiko,Furutani Toshiyuki,Imashiro Ritsuo,Kuroda Tooru,Yamanaka Takeshi,Harada Naoyuki,Arakawa Hiroaki,Kusama Mari,Hashiyama Tomiki

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference21 articles.

1. Synthesis of 1, 5-Benzothiazepine Derivatives. IV. Resolution of dl-cis-3-Acetoxy-5-[2-(dimethylamino)ethyl]-2, 3-dihydro-2-(p-methoxyphenyl)-1, 5-benzothiazepin-4(5H)-one Hydrochloride

2. Studies on a New 1, 5-Benzothiazepine Derivative (CRD-401). IV. Coronary Vasodilating Effect and Structure-Activity Relationship

3. Diltiazem Hydrochloride : Synthetic and Pharmacological Studies and Development

4. Reaction of 3-phenylglycidic esters. Part 1. Stereoselective opening of the oxirane ring of trans-3-phenylglycidic esters with 2-nitrothiophenols and the effect of various catalysts thereon

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1. Asymmetric reduction of 2-chloro-3-oxo-ester into enantiomerically high pure diltiazem precursor by a Candida ketoreductase;Molecular Catalysis;2021-06

2. Epoxide Syntheses and Ring-Opening Reactions in Drug Development;Catalysts;2020-09-27

3. Asymmetric catalysis in synthetic strategies for chiral benzothiazepines;Green Synthesis and Catalysis;2020-06

4. Hydroaminoalkylation/Buchwald-Hartwig amination sequences for the synthesis of benzo-annulated seven-membered nitrogen heterocycles;Tetrahedron;2019-08

5. Oxidation: Nobel Prize Chemistry Catalysis;Active Pharmaceutical Ingredients in Synthesis;2018-10-26

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