Synthesis of 4-phosphono(difluoromethyl)-D,L-phenylalanine and N-boc and N-Fmoc derivatives suitably protected for solid-phase synthesis of nonhydrolyzable phosphotyrosyl peptide analogues-Reference-Cited by-同舟云学术

Synthesis of 4-phosphono(difluoromethyl)-D,L-phenylalanine and N-boc and N-Fmoc derivatives suitably protected for solid-phase synthesis of nonhydrolyzable phosphotyrosyl peptide analogues

Published:1993-06 Issue:26 Volume:34 Page:4125-4128
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Burke Terrence R.,Smyth Mark S.,Otaka Akira,Roller Peter P.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference7 articles.

1. Preparation of 4-[Bis(tert-butoxy)phosphorylmethyl]-N-(fluoren-9-ylmethoxycarbonyl)-DL-phenylalanine. A Hydrolytically Stable Analogue ofO-Phosphotyrosine Potentially Suitable for Peptide Synthesis

2. Solid-phase synthesis of nonhydrolyzable phosphotyrosyl peptide analogues with Nα-Fmoc-(O,O-di-t-butyl)phosphono-p-methylphenylalanine

3. Inhibition of SH2 domain/phosphoprotein association by a nonhydrolyzable phosphonopeptide

4. A general method for the preparation of benzylic α,α-difluorophosphonic acids; non-hydrolyzable mimemtics of phosphotyrosine

5. Preparation of fluoro- and hydroxy-4-(phosphonomethyl)-D,L-phenylalanine suitably protected for solid-phase synthesis of peptides containing hydrolytically stable analogs of O-phosphotyrosine

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