Short, stereoselective syntheses of 4,5,6-trihydroxylated norleucines: An approach to the synthesis of (+)-bulgecinine
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference9 articles.
1. Preparation of enantiomerically pure protected 4-oxo .alpha.-amino acids and 3-aryl .alpha.-amino acids from serine
2. Vitamin C and isovitamin C derived chemistry. 2. Synthesis of some enantiomerically pure 4,5,6-trihydroxylated norleucines
3. Use of L-aspartic acid β-semialdehyde in the synthesis of more complex non protein amino acids
4. An efficient synthesis of (-)-bulgecinine
5. Synthesis of (S)-(+)-methyl .BETA.,.GAMMA.-dihydroxy-.ALPHA.-methylenebutyrate and (S)-(-)-tulipalin B.
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3. A practical route to enantiopure 3-hydroxy-pyrrolidines: application to a straightforward synthesis of (−)-bulgecinine;Tetrahedron Letters;2008-02
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