Synthesis of (2R, 6R)-(−)-2,6-lupetidine: 2,6-disubstituted piperidines as potentially useful “C2-symmetric” chiral reagents.-Reference-Cited by-同舟云学术

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Synthesis of (2R, 6R)-(−)-2,6-lupetidine: 2,6-disubstituted piperidines as potentially useful “C2-symmetric” chiral reagents.

Published:1990-01 Issue:23 Volume:31 Page:3279-3282
ISSN:0040-4039
Container-title:Tetrahedron Letters
language:en
Short-container-title:Tetrahedron Letters

Author:

Najdi Samir,Kurth Mark J

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference20 articles.

1. C2 symmetry and asymmetric induction

2. Asymmetric induction. 3. Enantioselective deprotonation by chiral lithium amide bases

3. Asymmetric acylation of carboxamides having -2,5-bis(methoxymethoxymethyl)pyrrolidine moiety as a chiral auxiliary and stereoselective reduction of the resulting 2-alkyl-3-oxoamides

4. Highly -diastereoselective reduction of 2-alkyl-3-oxo amides by potassium triethylborohydride

5. Asymmetric dialkylation of α-cyanoacetic acid

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